Date: January 24, 2025 | 14:00 CET
CCE Lecture
A Computational Framework for Personalized Modeling of the Vascular Microenvironment
to Predict Radiotherapy Outcomes in Head-and-Neck Cancer
Hosted by INT
Speaker: Dr. Tiziana Rancati
medical physics researcher, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Webex link:
https://istitutotumorimi.webex.com/istitutotumorimi-it/j.php?MTID=m1395ffa56b45fa8cf967706dfbada65e
This lecture explores the integration of clinical data with advanced biophysical models for microcirculation, presenting a framework that enables the creation of digital twins. These digital representations facilitate a bidirectional interaction between the model and the actual patient, offering a valuable tool for precision medicine.
By modeling the microvasculature of individual patients, this approach allows for detailed analysis of the microvascular environment and provides a platform for forecasting personalized radiotherapy outcomes.
Key aspects of the lecture include:
• The fundamental components of a biophysical model for microcirculation
• Methods for data collection and analysis to digitally represent patient-specific microvasculature
• Strategies for building personalized microvascular models
This framework highlights the potential of merging biophysical modeling with clinical data to advance patient-specific therapeutic strategies.
What is Cancer Core Europe (CCE)?
Cancer Core Europe is a consortium of seven leading cancer centres (www.cancercoreeurope.eu). CCEs members are driven by a strong will to reshape the cancer research model to ultimately increase the European Union’s competitiveness as a place to conduct cutting-edge research that’s translated to the clinic to deliver more personalized medicine.
