DKTK School of Oncology Tech Talk 

State of the Art in Immune Monitoring 
Dr. Isabel Poschke
Head of Immune Monitoring Unit at NCT Heidelberg and team lead within Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology (DKFZ)

December 14, 2026 (Virtual) 

Join our third and last DKTK School of Oncology Tech Talk in 2026 with Dr. Isabel Poschke who will talk about "State of the Art in Immune Monitoring". As per usual after the presentation there will be the opportunity to ask questions and to engage in a lively discussion. 

Immune monitoring has become an integral component of immuno-oncology trials, providing insights into treatment-induced immune responses and their relationship with clinical outcome. With increasingly sophisticated immunotherapeutic strategies, however, conventional measures of immune activation are often insufficient to capture the breadth, quality, and dynamics of treatment-induced T-cell responses.

The Immune Monitoring Unit (IMU) at the National Center for Tumor Diseases (NCT) in Heidelberg develops and implements advanced approaches for deep immune profiling in clinical trials. By integrating multiparametric flow cytometry, functional T-cell assays, T-cell receptor (TCR) repertoire sequencing, single-cell technologies, and antigen-specific TCR identification, we aim to resolve immune responses from global changes in immune composition down to individual antigen-reactive T-cell clonotypes.

During the seminar, we will review several immune assays, from basic to cutting-edge, evaluate their strengths and pitfalls, and discuss how they are being used in real-word immune-oncology trials.

Further information at https://indico.dkfz.de/event/1738/