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  1. MunichCancerTalks
  2. Devices
  3. All-In-One by Trasis // Radiochemistry Synthesizer

All-In-One by Trasis // Radiochemistry Synthesizer

AG Bartenstein, LMU Klinikum
Das All-In-One Synthesemodul (Fa. TRASIS) in einer Blei-abgeschirmten Synthesezelle (einer sog. „Heisszelle“, Ansicht bei geöffneter Zellentür) in einem Reinraum der Radiopharmazie

The synthesizer merges in a single integrated instrument a synthesizer and a HPLC with reformulation capability, which allows implementing both very simple and the most complex radiochemistry. If there is a need to evolve towards more complex tracers, the synthesizer can be upgraded to a different configuration model. The synthesizer includes 30 valves, HPLC, multiple radioactivity, and UV detection for GMP compliant routine production of 18F tracers and /or for R&D.


  • Contact
    Dr. Franz J. Gildehaus / 089 4400 69944 / franz.gildehaus@med.uni-muenchen.de
    Prof. Dr. Peter Bartenstein / 089 4400 74611 / peter.bartenstein@med.uni-muenchen.de

  • Location of device
    LMU Klinikum, Campus Großhadern
    Radiopharmacy Center, Building BT028, Marchioninistrasse 15, 81377 München
  • Costs
    In the synthesis module, a sample is equivalent to a synthesis run. The cost of doing so varies greatly depending on the complexity of the chemical synthesis to be performed, how expensive the starting components are, and how the GMP requirements are defined. Normally the costs / synthesis are between 800 € and 2.600 €.
  • Service
    Production of 18F-labeled compounds for in vivo PET imaging. These include:
    - Radiofluorinations of small molecules, peptides and biomolecules
    - development of labeling strategies
    - automation of radiosynthesis
    - GMP-compliant implementation

Munich Cancer Talks on behalf of

DKTK / Deutsches Konsortium für Translationale Krebsforschung Partnerstandort München

CCC München / Comprehensive Cancer Center München

BZKF / Bayerisches Zentrum für Krebsforschung Standort München

MRI / Klinikum rechts der Isar der Technischen Universität München

TUM / Technische Universität München

LMU Klinikum

LMU / Ludwig-Maximilians-Universität München

 

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